New study reveals the cellular network behind food tolerance, allergies

In infection, DCs chop up microbes and present their bits and pieces to other cells, triggering an assault by the immune system. The prevailing view of oral tolerance was that, after checking out digested food, DCs could instead decide to keep that attack at bay, instructing the immune cells to stand down and suppress any action.Yet, strangely, when researchers eliminated the suspected subset of DCs in animal models, oral tolerance still developed.